Monkey Organoid Complete Medium
Monkey Liver Organoid Complete Medium
Catalog Number: GBCM0075
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Product Specifications
| Product Name | Monkey Liver Organoid Complete Medium |
|---|---|
| Size | 100mL |
| Quality Control Standards | pH: 7.2~7.4Endotoxin content: <10 EU/mLBiosafety: Negative for bacteria, fungi, and mycoplasma detectionPerformance test: Passed organoid culture test |
| Storage Condition | Store at -20℃,valid for 6 months.Store at 2-8℃valid for 2 weeks.Once thawed, use immediately. Do not refreeze. Can be aliquoted and stored according to your needs. |
| Precautions | Upon receipt, store immediately in a -20°C freezer, or aliquot and store in a 2-8°C refrigerator.When unpacking, check for any leakage or damage.Use aseptic techniques during product handling to avoid contamination. |
Product Description
Cell Source and Tissue Characteristics:
The liver organoids of crab-eating monkeys are derived from adult liver stem cells/progenitor cells (ALSCs) in liver tissue, also known as hepatoblasts, which can be divided into hepatocytes and cholangiocytes.The liver is the body's main metabolic organ, responsible for drug metabolism, bile acid synthesis, protein synthesis and glycolipid metabolism.Monkey liver organoids are particularly suitable for drug metabolism enzyme research (CYP450 enzyme system) and drug-induced liver injury (DILI) prediction.In 2023, Jiang et al. established the liver ductal organoids of crab-eating monkeys and found that they showed the most significant expression of drug metabolism enzymes and transporter proteins among all tested organoids.The enzyme profile of CYP450 in the liver of non-human primates is highly similar to that of humans (especially the homology of CYP3A8 and human CYP3A4), and it is the "gold standard" animal model for drug metabolism research.
The liver organoids of crab-eating monkeys are derived from adult liver stem cells/progenitor cells (ALSCs) in liver tissue, also known as hepatoblasts, which can be divided into hepatocytes and cholangiocytes.The liver is the body's main metabolic organ, responsible for drug metabolism, bile acid synthesis, protein synthesis and glycolipid metabolism.Monkey liver organoids are particularly suitable for drug metabolism enzyme research (CYP450 enzyme system) and drug-induced liver injury (DILI) prediction.In 2023, Jiang et al. established the liver ductal organoids of crab-eating monkeys and found that they showed the most significant expression of drug metabolism enzymes and transporter proteins among all tested organoids.The enzyme profile of CYP450 in the liver of non-human primates is highly similar to that of humans (especially the homology of CYP3A8 and human CYP3A4), and it is the "gold standard" animal model for drug metabolism research.
Monkey Liver Organoid Complete Medium is a high-performance complete medium specifically designed for Monkey Liver Organoid culture. This advanced formulation employs optimized nutrient composition and growth factor cocktails to precisely mimic the in vivo tissue microenvironment, supporting long-term establishment, expansion, and maintenance of organoids from primary tissue samples.
Monkey Liver Organoid Complete Medium is suitable for multiple applications including precision medicine research, high-throughput drug screening, toxicity testing, developmental biology studies, and organoid biobanking. The product undergoes rigorous quality control including sterility testing, endotoxin detection, functional validation using established organoid lines, and batch-to-batch consistency checks.
Monkey Liver Organoid Complete Medium is suitable for multiple applications including precision medicine research, high-throughput drug screening, toxicity testing, developmental biology studies, and organoid biobanking. The product undergoes rigorous quality control including sterility testing, endotoxin detection, functional validation using established organoid lines, and batch-to-batch consistency checks.
Notes
- For research use only. Not for diagnostic or therapeutic procedures.
- All products undergo rigorous quality testing including sterility and performance validation.
- Contact our support team for protocol optimization and troubleshooting assistance.
- More validation data are prepared for uploading.