Mouse Organoid Differentiation Medium
Mouse Tongue Organoid Differentiation Medium
Catalog Number: GBCM0070
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Product Specifications
| Product Name | Mouse Tongue Organoid Differentiation Medium |
|---|---|
| Size | 100mL |
| Quality Control Standards | pH: 7.2~7.4Endotoxin content: <10 EU/mLBiosafety: Negative for bacteria, fungi, and mycoplasma detectionPerformance test: Passed organoid culture test |
| Storage Condition | Store at -20℃,valid for 6 months.Store at 2-8℃valid for 2 weeks.Once thawed, use immediately. Do not refreeze. Can be aliquoted and stored according to your needs. |
| Precautions | Upon receipt, store immediately in a -20°C freezer, or aliquot and store in a 2-8°C refrigerator.When unpacking, check for any leakage or damage.Use aseptic techniques during product handling to avoid contamination. |
Product Description
Cell Source and Tissue Characteristics:
Mouse tongue organoid differentiation medium is used to differentiate tongue epithelial stem cells into taste receptor cells (TRCs).The tongue organoids are derived from Lgr5+ stem cells from the mouse contour papillae (CVP) and foliate papillae (FoP).After differentiation, four taste cell types are produced: (1) Type I cells (glial-like cells)-expressing GLAST/NTPDase2; (2) Type II cells (receptor cells)-expressing PLCß2, TRPM5, GNAT3, responsible for sweetness, umami and bitter taste perception; (3) Type III cells (presynaptic cells)-expressing SNAP25, NCAM, with synaptic connections; (4) Type IV cells (precursor cells)-expressing Lgr5, SOX2.Wnt and Notch signals regulate the fate of taste cells.This differentiation system is suitable for the study of taste biology, taste disorders and taste phylogeny.
Mouse tongue organoid differentiation medium is used to differentiate tongue epithelial stem cells into taste receptor cells (TRCs).The tongue organoids are derived from Lgr5+ stem cells from the mouse contour papillae (CVP) and foliate papillae (FoP).After differentiation, four taste cell types are produced: (1) Type I cells (glial-like cells)-expressing GLAST/NTPDase2; (2) Type II cells (receptor cells)-expressing PLCß2, TRPM5, GNAT3, responsible for sweetness, umami and bitter taste perception; (3) Type III cells (presynaptic cells)-expressing SNAP25, NCAM, with synaptic connections; (4) Type IV cells (precursor cells)-expressing Lgr5, SOX2.Wnt and Notch signals regulate the fate of taste cells.This differentiation system is suitable for the study of taste biology, taste disorders and taste phylogeny.
Mouse Tongue Organoid Differentiation Medium is a high-performance complete medium specifically designed for Mouse Tongue Organoid culture. This advanced formulation employs optimized nutrient composition and growth factor cocktails to precisely mimic the in vivo tissue microenvironment, supporting long-term establishment, expansion, and maintenance of organoids from primary tissue samples.
Mouse Tongue Organoid Differentiation Medium is suitable for multiple applications including precision medicine research, high-throughput drug screening, toxicity testing, developmental biology studies, and organoid biobanking. The product undergoes rigorous quality control including sterility testing, endotoxin detection, functional validation using established organoid lines, and batch-to-batch consistency checks.
Mouse Tongue Organoid Differentiation Medium is suitable for multiple applications including precision medicine research, high-throughput drug screening, toxicity testing, developmental biology studies, and organoid biobanking. The product undergoes rigorous quality control including sterility testing, endotoxin detection, functional validation using established organoid lines, and batch-to-batch consistency checks.
Notes
- For research use only. Not for diagnostic or therapeutic procedures.
- All products undergo rigorous quality testing including sterility and performance validation.
- Contact our support team for protocol optimization and troubleshooting assistance.
- More validation data are prepared for uploading.