Mouse Organoid Differentiation Medium
Mouse Lung Organoid Differentiation Medium
Catalog Number: GBCM0069
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Product Specifications
| Product Name | Mouse Lung Organoid Differentiation Medium |
|---|---|
| Size | 100mL |
| Quality Control Standards | pH: 7.2~7.4Endotoxin content: <10 EU/mLBiosafety: Negative for bacteria, fungi, and mycoplasma detectionPerformance test: Passed organoid culture test |
| Storage Condition | Store at -20℃,valid for 6 months.Store at 2-8℃valid for 2 weeks.Once thawed, use immediately. Do not refreeze. Can be aliquoted and stored according to your needs. |
| Precautions | Upon receipt, store immediately in a -20°C freezer, or aliquot and store in a 2-8°C refrigerator.When unpacking, check for any leakage or damage.Use aseptic techniques during product handling to avoid contamination. |
Product Description
Cell Source and Tissue Characteristics:
Mouse pulmonary organoid differentiation medium is used to differentiate pulmonary bud tip progenitor cells or enlarged pulmonary organs into alveolar or airway lineages.Pulmonary bud tip progenitor cells (SOX2+/SOX9+/NKX2-1+) have two-way differentiation potential: (1) The direction of alveolar differentiation-the production of type II alveolar cells (AT2, SFTPC+/ABCA3+) and type I alveolar cells (AT1, AQP5+/HOPX+/PDPN+); (2) The direction of airway differentiation-the production of basal cells, epithelial cells, cup-shaped cells and ciliated cells.Alveolar differentiation requires Wnt activation and Notch inhibition, while airway differentiation requires precise regulation of SMAD signals.The differentiation system is suitable for the study of alveolar development, acute respiratory distress syndrome (ARDS), pulmonary fibrosis and repair of alveolar epithelial damage.
Mouse pulmonary organoid differentiation medium is used to differentiate pulmonary bud tip progenitor cells or enlarged pulmonary organs into alveolar or airway lineages.Pulmonary bud tip progenitor cells (SOX2+/SOX9+/NKX2-1+) have two-way differentiation potential: (1) The direction of alveolar differentiation-the production of type II alveolar cells (AT2, SFTPC+/ABCA3+) and type I alveolar cells (AT1, AQP5+/HOPX+/PDPN+); (2) The direction of airway differentiation-the production of basal cells, epithelial cells, cup-shaped cells and ciliated cells.Alveolar differentiation requires Wnt activation and Notch inhibition, while airway differentiation requires precise regulation of SMAD signals.The differentiation system is suitable for the study of alveolar development, acute respiratory distress syndrome (ARDS), pulmonary fibrosis and repair of alveolar epithelial damage.
Mouse Lung Organoid Differentiation Medium is a high-performance complete medium specifically designed for Mouse Lung Organoid culture. This advanced formulation employs optimized nutrient composition and growth factor cocktails to precisely mimic the in vivo tissue microenvironment, supporting long-term establishment, expansion, and maintenance of organoids from primary tissue samples.
Mouse Lung Organoid Differentiation Medium is suitable for multiple applications including precision medicine research, high-throughput drug screening, toxicity testing, developmental biology studies, and organoid biobanking. The product undergoes rigorous quality control including sterility testing, endotoxin detection, functional validation using established organoid lines, and batch-to-batch consistency checks.
Mouse Lung Organoid Differentiation Medium is suitable for multiple applications including precision medicine research, high-throughput drug screening, toxicity testing, developmental biology studies, and organoid biobanking. The product undergoes rigorous quality control including sterility testing, endotoxin detection, functional validation using established organoid lines, and batch-to-batch consistency checks.
Notes
- For research use only. Not for diagnostic or therapeutic procedures.
- All products undergo rigorous quality testing including sterility and performance validation.
- Contact our support team for protocol optimization and troubleshooting assistance.
- More validation data are prepared for uploading.