Mouse Organoid Differentiation Medium
Mouse Liver Organoid Differentiation Medium
Catalog Number: GBCM0068
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Product Specifications
| Product Name | Mouse Liver Organoid Differentiation Medium |
|---|---|
| Size | 100mL |
| Quality Control Standards | pH: 7.2~7.4Endotoxin content: <10 EU/mLBiosafety: Negative for bacteria, fungi, and mycoplasma detectionPerformance test: Passed organoid culture test |
| Storage Condition | Store at -20℃,valid for 6 months.Store at 2-8℃valid for 2 weeks.Once thawed, use immediately. Do not refreeze. Can be aliquoted and stored according to your needs. |
| Precautions | Upon receipt, store immediately in a -20°C freezer, or aliquot and store in a 2-8°C refrigerator.When unpacking, check for any leakage or damage.Use aseptic techniques during product handling to avoid contamination. |
Product Description
Cell Source and Tissue Characteristics:
Mouse liver organoid differentiation medium is used to differentiate liver progenitor cell organoids in the direction of mature liver cells (hepatocyte).Mouse liver organoids are derived from EpCAM+ bile duct cells or Lgr5+ liver stem cells, and maintain progenitor cell status under amplification conditions (expressing PROM1, AXIN2, SOX9, CD44, KRT19).After differentiation, the cells acquire the characteristics of mature liver cells, express albumin (Albumin/ALB), HNF4a, CYP450 family metabolic enzymes, α1-antitrypsin (AAT), etc., and have functions such as albumin secretion, cytochrome metabolic activity, and bile acid production.Notch signal inhibition is the key to driving liver cell differentiation.The differentiation system is suitable for drug metabolism research, toxicological testing and liver disease modeling.
Mouse liver organoid differentiation medium is used to differentiate liver progenitor cell organoids in the direction of mature liver cells (hepatocyte).Mouse liver organoids are derived from EpCAM+ bile duct cells or Lgr5+ liver stem cells, and maintain progenitor cell status under amplification conditions (expressing PROM1, AXIN2, SOX9, CD44, KRT19).After differentiation, the cells acquire the characteristics of mature liver cells, express albumin (Albumin/ALB), HNF4a, CYP450 family metabolic enzymes, α1-antitrypsin (AAT), etc., and have functions such as albumin secretion, cytochrome metabolic activity, and bile acid production.Notch signal inhibition is the key to driving liver cell differentiation.The differentiation system is suitable for drug metabolism research, toxicological testing and liver disease modeling.
Mouse Liver Organoid Differentiation Medium is a high-performance complete medium specifically designed for Mouse Liver Organoid culture. This advanced formulation employs optimized nutrient composition and growth factor cocktails to precisely mimic the in vivo tissue microenvironment, supporting long-term establishment, expansion, and maintenance of organoids from primary tissue samples.
Mouse Liver Organoid Differentiation Medium is suitable for multiple applications including precision medicine research, high-throughput drug screening, toxicity testing, developmental biology studies, and organoid biobanking. The product undergoes rigorous quality control including sterility testing, endotoxin detection, functional validation using established organoid lines, and batch-to-batch consistency checks.
Mouse Liver Organoid Differentiation Medium is suitable for multiple applications including precision medicine research, high-throughput drug screening, toxicity testing, developmental biology studies, and organoid biobanking. The product undergoes rigorous quality control including sterility testing, endotoxin detection, functional validation using established organoid lines, and batch-to-batch consistency checks.
Notes
- For research use only. Not for diagnostic or therapeutic procedures.
- All products undergo rigorous quality testing including sterility and performance validation.
- Contact our support team for protocol optimization and troubleshooting assistance.
- More validation data are prepared for uploading.