Mouse Organoid Complete Medium
Mouse Esophageal Organoid Complete Medium
Catalog Number: GBCM0052
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Product Specifications
| Product Name | Mouse Esophageal Organoid Complete Medium |
|---|---|
| Size | 100mL |
| Quality Control Standards | pH: 7.2~7.4Endotoxin content: <10 EU/mLBiosafety: Negative for bacteria, fungi, and mycoplasma detectionPerformance test: Passed organoid culture test |
| Storage Condition | Store at -20℃,valid for 6 months.Store at 2-8℃valid for 2 weeks.Once thawed, use immediately. Do not refreeze. Can be aliquoted and stored according to your needs. |
| Precautions | Upon receipt, store immediately in a -20°C freezer, or aliquot and store in a 2-8°C refrigerator.When unpacking, check for any leakage or damage.Use aseptic techniques during product handling to avoid contamination. |
Product Description
Cell Source and Tissue Characteristics:
Mouse esophageal organoids are derived from basal stem cells of the esophageal epithelium of mice.The esophageal epithelium is a laminated flat epithelium, similar to the skin epidermis, and its stem cells express markers such as BMI1, SOX2, and TP63.Esophageal organoids can be amplified from single-cell clones under minimum medium conditions, and histological and transcriptome analysis prove that they are equivalent to the esophageal epithelium in vivo.Through Trp53 knock-out and KrasG12D expression, esophageal squamous intraepithelial neoplasia (early lesions of ESCC) can be induced in organoids, and the first organoid model of ESCC occurrence is established.
Mouse esophageal organoids are derived from basal stem cells of the esophageal epithelium of mice.The esophageal epithelium is a laminated flat epithelium, similar to the skin epidermis, and its stem cells express markers such as BMI1, SOX2, and TP63.Esophageal organoids can be amplified from single-cell clones under minimum medium conditions, and histological and transcriptome analysis prove that they are equivalent to the esophageal epithelium in vivo.Through Trp53 knock-out and KrasG12D expression, esophageal squamous intraepithelial neoplasia (early lesions of ESCC) can be induced in organoids, and the first organoid model of ESCC occurrence is established.
Mouse Esophageal Organoid Complete Medium is a high-performance complete medium specifically designed for Mouse Esophageal Organoid culture. This advanced formulation employs optimized nutrient composition and growth factor cocktails to precisely mimic the in vivo tissue microenvironment, supporting long-term establishment, expansion, and maintenance of organoids from primary tissue samples.
Mouse Esophageal Organoid Complete Medium is suitable for multiple applications including precision medicine research, high-throughput drug screening, toxicity testing, developmental biology studies, and organoid biobanking. The product undergoes rigorous quality control including sterility testing, endotoxin detection, functional validation using established organoid lines, and batch-to-batch consistency checks.
Mouse Esophageal Organoid Complete Medium is suitable for multiple applications including precision medicine research, high-throughput drug screening, toxicity testing, developmental biology studies, and organoid biobanking. The product undergoes rigorous quality control including sterility testing, endotoxin detection, functional validation using established organoid lines, and batch-to-batch consistency checks.
Notes
- For research use only. Not for diagnostic or therapeutic procedures.
- All products undergo rigorous quality testing including sterility and performance validation.
- Contact our support team for protocol optimization and troubleshooting assistance.
- More validation data are prepared for uploading.