Human Organoid Differentiation Medium
Human Lung Organoid Differentiation Medium
Catalog Number: GBCM0046
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Product Specifications
| Product Name | Human Lung Organoid Differentiation Medium |
|---|---|
| Size | 100mL |
| Quality Control Standards | pH: 7.2~7.4Endotoxin content: <10 EU/mLBiosafety: Negative for bacteria, fungi, and mycoplasma detectionPerformance test: Passed organoid culture test |
| Storage Condition | Store at -20℃,valid for 6 months.Store at 2-8℃valid for 2 weeks.Once thawed, use immediately. Do not refreeze. Can be aliquoted and stored according to your needs. |
| Precautions | Upon receipt, store immediately in a -20°C freezer, or aliquot and store in a 2-8°C refrigerator.When unpacking, check for any leakage or damage.Use aseptic techniques during product handling to avoid contamination. |
Product Description
Cell Source and Tissue Characteristics:
Human pulmonary organoid differentiation medium is used to induce differentiation of pulmonary stem cells or pulmonary bud progenitor cells into functional alveolar and/or airway cell types.The direction of differentiation depends on the medium formula: the distal differentiation scheme (distal differentiation) produces alveolar organoids, including AT2 cells (SFTPC+/HTII-280+/ABCA3+) and AT1 cells (AQP5+/PDPN+/HOPX+); the proximal differentiation scheme (proximal differentiation) produces airway organoids, including basal cells, ciliated cells, and cup-shaped cells.The key to alveolar differentiation is to simulate the differentiation process of AT2 cells to AT1 cells, which is the core mechanism of alveolar regeneration and repair.Barkauskas et al. (2013) demonstrated for the first time that AEC2 is an alveolar stem cell that can self-renew and differentiate into AEC1.
Human pulmonary organoid differentiation medium is used to induce differentiation of pulmonary stem cells or pulmonary bud progenitor cells into functional alveolar and/or airway cell types.The direction of differentiation depends on the medium formula: the distal differentiation scheme (distal differentiation) produces alveolar organoids, including AT2 cells (SFTPC+/HTII-280+/ABCA3+) and AT1 cells (AQP5+/PDPN+/HOPX+); the proximal differentiation scheme (proximal differentiation) produces airway organoids, including basal cells, ciliated cells, and cup-shaped cells.The key to alveolar differentiation is to simulate the differentiation process of AT2 cells to AT1 cells, which is the core mechanism of alveolar regeneration and repair.Barkauskas et al. (2013) demonstrated for the first time that AEC2 is an alveolar stem cell that can self-renew and differentiate into AEC1.
Human Lung Organoid Differentiation Medium is a high-performance complete medium specifically designed for Human Lung Organoid culture. This advanced formulation employs optimized nutrient composition and growth factor cocktails to precisely mimic the in vivo tissue microenvironment, supporting long-term establishment, expansion, and maintenance of organoids from primary tissue samples.
Human Lung Organoid Differentiation Medium is suitable for multiple applications including precision medicine research, high-throughput drug screening, toxicity testing, developmental biology studies, and organoid biobanking. The product undergoes rigorous quality control including sterility testing, endotoxin detection, functional validation using established organoid lines, and batch-to-batch consistency checks.
Human Lung Organoid Differentiation Medium is suitable for multiple applications including precision medicine research, high-throughput drug screening, toxicity testing, developmental biology studies, and organoid biobanking. The product undergoes rigorous quality control including sterility testing, endotoxin detection, functional validation using established organoid lines, and batch-to-batch consistency checks.
Notes
- For research use only. Not for diagnostic or therapeutic procedures.
- All products undergo rigorous quality testing including sterility and performance validation.
- Contact our support team for protocol optimization and troubleshooting assistance.
- More validation data are prepared for uploading.