Human Organoid Differentiation Medium
Human Intestinal Organoid Differentiation Medium
Catalog Number: GBCM0044
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Product Specifications
| Product Name | Human Intestinal Organoid Differentiation Medium |
|---|---|
| Size | 100mL |
| Quality Control Standards | pH: 7.2~7.4Endotoxin content: <10 EU/mLBiosafety: Negative for bacteria, fungi, and mycoplasma detectionPerformance test: Passed organoid culture test |
| Storage Condition | Store at -20℃,valid for 6 months.Store at 2-8℃valid for 2 weeks.Once thawed, use immediately. Do not refreeze. Can be aliquoted and stored according to your needs. |
| Precautions | Upon receipt, store immediately in a -20°C freezer, or aliquot and store in a 2-8°C refrigerator.When unpacking, check for any leakage or damage.Use aseptic techniques during product handling to avoid contamination. |
Product Description
Cell Source and Tissue Characteristics:
Intestinal organoid differentiation culture aims to induce differentiation of enlarged intestinal organoids (rich in Lgr5+ stem cells) into organoids containing all mature intestinal epithelial cell types, including intestinal epithelial cells (Enterocytes, responsible for nutrient absorption), goblet cells (Goblet cells, secreting mucus), Paneth cells (Paneth cells, secreting antibacterial peptides) and enteroendocrine cells (Enteroendocrine cells, secreting hormones).This differentiation process simulates the natural process in the body from the stem cell area at the bottom of the crypt to the differentiation area at the top of the villi.The differentiated intestinal organoids can be used to study nutrient absorption, drug metabolism, barrier function, host-microbial interaction, and infectious diseases.
Intestinal organoid differentiation culture aims to induce differentiation of enlarged intestinal organoids (rich in Lgr5+ stem cells) into organoids containing all mature intestinal epithelial cell types, including intestinal epithelial cells (Enterocytes, responsible for nutrient absorption), goblet cells (Goblet cells, secreting mucus), Paneth cells (Paneth cells, secreting antibacterial peptides) and enteroendocrine cells (Enteroendocrine cells, secreting hormones).This differentiation process simulates the natural process in the body from the stem cell area at the bottom of the crypt to the differentiation area at the top of the villi.The differentiated intestinal organoids can be used to study nutrient absorption, drug metabolism, barrier function, host-microbial interaction, and infectious diseases.
Human Intestinal Organoid Differentiation Medium is a high-performance complete medium specifically designed for Human Intestinal Organoid culture. This advanced formulation employs optimized nutrient composition and growth factor cocktails to precisely mimic the in vivo tissue microenvironment, supporting long-term establishment, expansion, and maintenance of organoids from primary tissue samples.
Human Intestinal Organoid Differentiation Medium is suitable for multiple applications including precision medicine research, high-throughput drug screening, toxicity testing, developmental biology studies, and organoid biobanking. The product undergoes rigorous quality control including sterility testing, endotoxin detection, functional validation using established organoid lines, and batch-to-batch consistency checks.
Human Intestinal Organoid Differentiation Medium is suitable for multiple applications including precision medicine research, high-throughput drug screening, toxicity testing, developmental biology studies, and organoid biobanking. The product undergoes rigorous quality control including sterility testing, endotoxin detection, functional validation using established organoid lines, and batch-to-batch consistency checks.
Notes
- For research use only. Not for diagnostic or therapeutic procedures.
- All products undergo rigorous quality testing including sterility and performance validation.
- Contact our support team for protocol optimization and troubleshooting assistance.
- More validation data are prepared for uploading.